|
KMID : 1007320170230010001
|
|
Journal of the Korean Society of Menopause
2017 Volume.23 No. 1 p.1 ~ p.4
|
|
|
Cell Therapy Products in Alzheimer Disease
|
|
Song Hyeon-Jin
Kim Tae-Hee
Lee Hae-Hyeog
Kim Jun-Mo
Park Yoo-Jin
Lee A-Rum
Kim Soo-Ah
Choi Hye-Ji
|
|
|
Abstract
|
|
|
|
We are rapidly becoming an aging society, with the ongoing increase in challenges of the elderly. The age-related cognitive decline in accordance with aging society is of major importance in public health. Recent studies have proved the impacts of sexsteroid hormone on the brain; compliant with aging, menopause and decrease in estrogen have an effect on the occurrence and prevention of Alzheimer’s disease. A new hypothesis states that Alzheimer’s disease is a postmenopausal dementia, and is a negative form of estrogen deficiency. In this review article, we reckoned the cause of postmenopausal Alzheimer’s disease. We further investigated new cell therapies for postmenopausal Alzheimer’s disease, which are under development in some pharmaceutical companies. One remedy is cell therapy that inhibits the amyloid beta formation, and the other is the umbilical cord blood derived mesenchymal stem cell therapy.
|
|
|
KEYWORD
|
|
|
Alzheimer’s disease, Cell- and tissue-based therapy, Menopause, Stem cells
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|